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Elevated Sensitivity of Macrosteatotic Hepatocytes to Hypoxia-Reoxygenation Stress Is Reversed by a Novel Defatting Protocol
Macrosteatotic livers exhibit elevated intrahepatic triglyceride (TG) content in the form of large lipid droplets (LDs), reduced ATP, and elevated reactive oxygen species (ROS), contributing to their elevated sensitivity to ischemia-reperfusion injury during transplantation. Decreasing macrosteatosi...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4117728/ https://ncbi.nlm.nih.gov/pubmed/24802973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lt.23905 |
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