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Leveraging structure for enzyme function prediction: methods, opportunities and challenges

The rapid growth of the number of protein sequences that can be inferred from sequenced genomes presents challenges for function assignment, as only a small fraction (currently <%) of have been experimentally characterized. Bioinformatics tools are commonly used to predict functions of uncharacte...

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Detalhes bibliográficos
Main Authors: Jacobson, Matthew P., Kalyanaraman, Chakrapani, Zhao, Suwen, Tian, Boxue
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117707/
https://ncbi.nlm.nih.gov/pubmed/24998033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2014.05.006
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