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Studying enzyme-substrate specificity in silico: A case study of the E. coli glycolysis pathway

In silico protein-ligand docking methods have proved useful in drug design and have also shown promise for predicting the substrates of enzymes, an important goal given the number of enzymes with uncertain function. Further testing of this latter approach is critical because 1) metabolites are on av...

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Detalhes bibliográficos
Main Authors: Kalyanaraman, Chakrapani, Jacobson, Matthew P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877507/
https://ncbi.nlm.nih.gov/pubmed/20415432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100445g
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