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Primary defect of insulin receptors in skin fibroblasts cultured from an infant with leprechaunism and insulin resistance.

Insulin binding to insulin receptors, on skin fibroblasts established in culture from an infant with insulin resistance and clinical features of leprechaunism was markedly decreased in comparison with cultures from an age-matched control. By contrast, the binding of epidermal growth factor, a polype...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Schilling, E E, Rechler, M M, Grunfeld, C, Rosenberg, A M
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1979
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411755/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/293690/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.11.5877
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