Primary defect of insulin receptors in skin fibroblasts cultured from an infant with leprechaunism and insulin resistance.
Insulin binding to insulin receptors, on skin fibroblasts established in culture from an infant with insulin resistance and clinical features of leprechaunism was markedly decreased in comparison with cultures from an age-matched control. By contrast, the binding of epidermal growth factor, a polype...
Gespeichert in:
| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1979
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411755/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/293690/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.11.5877 |
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