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Receptors for insulinlike growth factor I are defective in fibroblasts cultured from a patient with leprechaunism.

We previously have demonstrated that fibroblasts from a patient with leprechaunism exhibited markedly decreased insulin binding to insulin receptors and that the ability of insulin to stimulate glucose incorporation in the patient's cells was greatly impaired. In addition, the insulinlike growt...

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Bibliografski detalji
Izdano u:J Clin Invest
Glavni autori: Van Obberghen-Schilling, E E, Rechler, M M, Romanus, J A, Knight, A B, Nissley, S P, Humbel, R E
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 1981
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370932/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6271812/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110383
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