Receptors for insulinlike growth factor I are defective in fibroblasts cultured from a patient with leprechaunism.

We previously have demonstrated that fibroblasts from a patient with leprechaunism exhibited markedly decreased insulin binding to insulin receptors and that the ability of insulin to stimulate glucose incorporation in the patient's cells was greatly impaired. In addition, the insulinlike growth fac...

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Detalles Bibliográficos

Publicado en:	J Clin Invest
Autores principales:	Van Obberghen-Schilling, E E, Rechler, M M, Romanus, J A, Knight, A B, Nissley, S P, Humbel, R E
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Clinical Investigation 1981
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370932/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6271812/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110383
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