Receptors for insulinlike growth factor I are defective in fibroblasts cultured from a patient with leprechaunism.

We previously have demonstrated that fibroblasts from a patient with leprechaunism exhibited markedly decreased insulin binding to insulin receptors and that the ability of insulin to stimulate glucose incorporation in the patient's cells was greatly impaired. In addition, the insulinlike growth fac...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Van Obberghen-Schilling, E E, Rechler, M M, Romanus, J A, Knight, A B, Nissley, S P, Humbel, R E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1981
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370932/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6271812/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110383
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