The Tyrosine Kinase Pyk2 Mediates Lipopolysaccharide-Induced IL-8 Expression in Human Endothelial Cells()

Secretion of proinflammatory cytokines by LPS activated endothelial cells contributes substantially to the pathogenesis of sepsis. However, the mechanism involved in this process is not well understood. In the present study, we determined the role of a nonreceptor proline-rich tyrosine kinase, Pyk2,...

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Bibliographic Details
Main Authors: Anand, Appakkudal R., Cucchiarini, Magali, Terwilliger, Ernest F., Ganju, Ramesh K.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117313/
https://ncbi.nlm.nih.gov/pubmed/18390748
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