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Activation of Autophagy by Inflammatory Signals Limits IL-1β Production by Targeting Ubiquitinated Inflammasomes for Destruction
Autophagosomes delivers cytoplasmic constituents to lysosomes for degradation while inflammasomes are molecular platforms activated by infection or stress that regulate the activity of caspase-1 and the maturation of interleukin 1β (IL-1β) and IL-18. Here we show that the induction of AIM2 or NLRP3...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4116819/ https://ncbi.nlm.nih.gov/pubmed/22286270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2215 |
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