Vaccine-Induced Env V1–V2 IgG3 Correlates with Lower HIV-1 Infection Risk and Declines Soon After Vaccination

HIV-1–specific immunoglobulin G (IgG) subclass antibodies bind to distinct cellular Fc receptors. Antibodies of the same epitope specificity but of a different subclass therefore can have different antibody effector functions. The study of IgG subclass profiles between different vaccine regimens use...

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Détails bibliographiques
Auteurs principaux: Yates, Nicole L., Liao, Hua-Xin, Fong, Youyi, deCamp, Allan, Vandergrift, Nathan A., Williams, William T., Alam, S. Munir, Ferrari, Guido, Yang, Zhi-yong, Seaton, Kelly E., Berman, Phillip W., Alpert, Michael D., Evans, David T., O’Connell, Robert J., Francis, Donald, Sinangil, Faruk, Lee, Carter, Nitayaphan, Sorachai, Rerks-Ngarm, Supachai, Kaewkungwal, Jaranit, Pitisuttithum, Punnee, Tartaglia, James, Pinter, Abraham, Zolla-Pazner, Susan, Gilbert, Peter B., Nabel, Gary J., Michael, Nelson L., Kim, Jerome H., Montefiori, David C., Haynes, Barton F., Tomaras, Georgia D.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116665/
https://ncbi.nlm.nih.gov/pubmed/24648342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3007730
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