Mycophenolic Acid Glucuronide (MPAG) is Transported by Multidrug Resistance-Associated Protein 2 (MRP2) and this Transport is not Inhibited by Cyclosporine, Tacrolimus or Sirolimus

1. The purpose of this study was to investigate the contribution of MRP2 to the efflux of mycophenolic acid (MPA), and its phenyl glucuronide (MPAG) and acyl glucuronide (AcMPAG) metabolites, using Madin-Darby canine kidney II cells stably transfected with human MRP2 gene (MDCKII/MRP2 cells). 2. Com...

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Hlavní autoři: Patel, Chirag G., Ogasawara, Ken, Akhlaghi, Fatemeh
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116557/
https://ncbi.nlm.nih.gov/pubmed/22934787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/00498254.2012.713531
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