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Regional haemodynamic effects of cyclosporine A, tacrolimus and sirolimus in conscious rats

1. The observation that the immunosuppressants, cyclosporine A (CsA) and tacrolimus, have pressor effects, but sirolimus does not, has led to an hypothesis that generalised sympathoexcitation, resulting from inhibition of calcineurin by CsA and tacrolimus underlies their pressor effects, because sir...

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Detalhes bibliográficos
Main Authors: Gardiner, S M, March, J E, Kemp, P A, Fallgren, B, Bennett, T
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574241/
https://ncbi.nlm.nih.gov/pubmed/14744807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705659
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