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Regional haemodynamic effects of cyclosporine A, tacrolimus and sirolimus in conscious rats

1. The observation that the immunosuppressants, cyclosporine A (CsA) and tacrolimus, have pressor effects, but sirolimus does not, has led to an hypothesis that generalised sympathoexcitation, resulting from inhibition of calcineurin by CsA and tacrolimus underlies their pressor effects, because sir...

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Main Authors: Gardiner, S M, March, J E, Kemp, P A, Fallgren, B, Bennett, T
Format: Artigo
Jezik:Inglês
Izdano: 2004
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574241/
https://ncbi.nlm.nih.gov/pubmed/14744807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705659
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