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Regional haemodynamic effects of cyclosporine A, tacrolimus and sirolimus in conscious rats

1. The observation that the immunosuppressants, cyclosporine A (CsA) and tacrolimus, have pressor effects, but sirolimus does not, has led to an hypothesis that generalised sympathoexcitation, resulting from inhibition of calcineurin by CsA and tacrolimus underlies their pressor effects, because sir...

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Dettagli Bibliografici
Autori principali: Gardiner, S M, March, J E, Kemp, P A, Fallgren, B, Bennett, T
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574241/
https://ncbi.nlm.nih.gov/pubmed/14744807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705659
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