The targeting mechanism of DHA ligand and its conjugate with Gemcitabine for the enhanced tumor therapy

Docosahexaenoic acid (DHA), an omega-3 C22 natural fatty acid serving as a precursor for metabolic and biochemical pathways, was reported as a targeting ligand of anticancer drugs. However, its tumor targeting ability and mechanism has not been claimed. Here we hypothesized that the uptake of DHA by...

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Библиографические подробности
Главные авторы: Li, Siwen, Qin, Jingyi, Tian, Caiping, Cao, Jie, Fida, Guissi, Wang, Zhaohui, Chen, Haiyan, Qian, Zhiyu, Chen, Wei R, Gu, Yueqing
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2014
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116508/
https://ncbi.nlm.nih.gov/pubmed/25004114
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