Novel harmine derivatives for tumor targeted therapy

Harmine is a beta-carboline alkaloid found in medicinal plant PeganumHarmala, which has served as a folk anticancer medicine. However, clinical applications of harmine were limited by its low pharmacological effects and noticeable neurotoxicity. In this study, we modified harmine to increase the the...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Li, Siwen, Wang, Aqin, Gu, Fan, Wang, Zhaohui, Tian, Caiping, Qian, Zhiyu, Tang, Liping, Gu, Yueqing
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4496197/
https://ncbi.nlm.nih.gov/pubmed/25940702
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