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Dual target gene therapy to EML4-ALK NSCLC by a gold nanoshell-based system
Although EML4-ALK transforming fusion gene is represented in only 8% of non-small cell lung cancer (NSCLC) cases, its expression is partly responsive for the failure of current NSCLC treatments. Preventing secondary mutation of the ALK protein through direct gene manipulation could overcome NSCLC dr...
Guardat en:
| Publicat a: | Theranostics |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Ivyspring International Publisher
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5956997/ https://ncbi.nlm.nih.gov/pubmed/29774063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.24469 |
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