Dual target gene therapy to EML4-ALK NSCLC by a gold nanoshell-based system

Although EML4-ALK transforming fusion gene is represented in only 8% of non-small cell lung cancer (NSCLC) cases, its expression is partly responsive for the failure of current NSCLC treatments. Preventing secondary mutation of the ALK protein through direct gene manipulation could overcome NSCLC dr...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Theranostics
Main Authors: Li, Siwen, Liu, Yuxi, Rui, Yalan, Tang, Liping, Achilefu, Samuel, Gu, Yueqing
Format: Artigo
Jezik:Inglês
Izdano: Ivyspring International Publisher 2018
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5956997/
https://ncbi.nlm.nih.gov/pubmed/29774063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.24469
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