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Activation of mTORC1 signaling and protein synthesis in human muscle following blood flow restriction exercise is inhibited by rapamycin

Restriction of blood flow to a contracting muscle during low-intensity resistance exercise (BFR exercise) stimulates mTORC1 signaling and protein synthesis in human muscle within 3 h postexercise. However, there is a lack of mechanistic data to provide a direct link between mTORC1 activation and pro...

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Autors principals: Gundermann, David M., Walker, Dillon K., Reidy, Paul T., Borack, Michael S., Dickinson, Jared M., Volpi, Elena, Rasmussen, Blake B.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116405/
https://ncbi.nlm.nih.gov/pubmed/24691032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00600.2013
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