Early activation of matrix metalloproteinases underlies the exacerbated systolic and diastolic dysfunction in mice lacking TIMP3 following myocardial infarction

Extracellular matrix (ECM) remodeling is a critical aspect of cardiac remodeling following myocardial infarction. Tissue inhibitors of metalloproteinases (TIMPs) are physiological inhibitors of matrix metalloproteinases (MMPs) that degrade the ECM proteins. TIMP3 is highly expressed in the heart, an...

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Detaylı Bibliyografya
Asıl Yazarlar: Kandalam, Vijay, Basu, Ratnadeep, Abraham, Thomas, Wang, Xiuhua, Awad, Ahmed, Wang, Wei, Lopaschuk, Gary D., Maeda, Nobuyo, Oudit, Gavin Y., Kassiri, Zamaneh
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2010
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Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116393/
https://ncbi.nlm.nih.gov/pubmed/20675565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00246.2010
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