ロード中...

Structure of a Dihydroxycoumarin Active-Site Inhibitor in Complex with the RNase H Domain of HIV-1 Reverse Transcriptase and Structure-Activity Analysis of Inhibitor Analogs

HIV encodes four essential enzymes: protease, integrase, reverse transcriptase (RT) associated DNA polymerase, and RT-associated ribonuclease H (RNase H). Current clinically approved anti-AIDS drugs target all HIV enzymatic activities except RNase H, which has proven to be a very difficult target fo...

詳細記述

保存先:
書誌詳細
主要な著者: Himmel, Daniel M., Myshakina, Nataliya S., Ilina, Tatiana, Van Ry, Alexander, Ho, William C., Parniak, Michael A., Arnold, Eddy
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116331/
https://ncbi.nlm.nih.gov/pubmed/24840303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2014.05.006
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!