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The importance of the lipoxygenase-hepoxilin pathway in the mammalian epidermal barrier
This review covers the background to discovery of the two key lipoxygenases (LOX) involved in epidermal barrier function, 12R-LOX and eLOX3, and our current views on their functioning. In the outer epidermis, their consecutive actions oxidize linoleic acid esterified in ω-hydroxy-ceramide to a hepox...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4116325/ https://ncbi.nlm.nih.gov/pubmed/24021977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2013.08.020 |
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