Cloned pairs of variable region genes for immunoglobulin heavy chains isolated from a clone library of the entire mouse genome.

To investigate the organization of immunoglobulin genes, we have constructed a clone library containing 10(6) randomly generated fragments of mouse embryo DNA, corresponding to eight equivalents of the genome. The cloning method involved methylation of embryo DNA at EcoRI recognition sites, partial...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Kemp, D J, Cory, S, Adams, J M
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 1979
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411632/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/116236/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.9.4627
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