Cloned pairs of variable region genes for immunoglobulin heavy chains isolated from a clone library of the entire mouse genome.
To investigate the organization of immunoglobulin genes, we have constructed a clone library containing 10(6) randomly generated fragments of mouse embryo DNA, corresponding to eight equivalents of the genome. The cloning method involved methylation of embryo DNA at EcoRI recognition sites, partial...
Shranjeno v:
| izdano v: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
1979
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411632/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/116236/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.9.4627 |
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