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Cloned pairs of variable region genes for immunoglobulin heavy chains isolated from a clone library of the entire mouse genome.

To investigate the organization of immunoglobulin genes, we have constructed a clone library containing 10(6) randomly generated fragments of mouse embryo DNA, corresponding to eight equivalents of the genome. The cloning method involved methylation of embryo DNA at EcoRI recognition sites, partial...

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Bibliografske podrobnosti
Main Authors: Kemp, D J, Cory, S, Adams, J M
Format: Artigo
Jezik:Inglês
Izdano: 1979
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC411632/
https://ncbi.nlm.nih.gov/pubmed/116236
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