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Characterization of alkylamine-sensitive site in alpha 2-macroglobulin.

Methylamine reacts with the plasma protease inhibitor, alpha 2-macroglobulin, to form an irreversible, covalent modification. Quantitation of the reaction indicates 3.9 +/- (SD) 0.4 reactive sites per native tetrameric protein (Mr = 725,000) or one site per subunit. The reaction is selective and spe...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Swenson, R P, Howard, J B
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1979
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411564/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/92026/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.9.4313
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