Characterization of alkylamine-sensitive site in alpha 2-macroglobulin.
Methylamine reacts with the plasma protease inhibitor, alpha 2-macroglobulin, to form an irreversible, covalent modification. Quantitation of the reaction indicates 3.9 +/- (SD) 0.4 reactive sites per native tetrameric protein (Mr = 725,000) or one site per subunit. The reaction is selective and spe...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1979
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411564/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/92026/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.9.4313 |
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