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Evidence for presence of an internal thiolester bond in third component of human complement.

Treatment of the third component of human complement (C3) with methylamine results in a loss of hemolytic function and the appearance of a thiol group. Studies with [14C]methylamine have indicatd a stoichiometric and covalent reaction with the native protein. Hydrazine-inactivated C3 and C3b prepare...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Tack, B F, Harrison, R A, Janatova, J, Thomas, M L, Prahl, J W
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC350151/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6934510/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.10.5764
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