Evidence for presence of an internal thiolester bond in third component of human complement.

Treatment of the third component of human complement (C3) with methylamine results in a loss of hemolytic function and the appearance of a thiol group. Studies with [14C]methylamine have indicatd a stoichiometric and covalent reaction with the native protein. Hydrazine-inactivated C3 and C3b prepare...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Tack, B F, Harrison, R A, Janatova, J, Thomas, M L, Prahl, J W
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1980
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC350151/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6934510/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.10.5764
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