Tumor suppressor p53 cooperates with SIRT6 to regulate gluconeogenesis by promoting FoxO1 nuclear exclusion

In mammalian cells, tumor suppressor p53 plays critical roles in the regulation of glucose metabolism, including glycolysis and oxidative phosphorylation, but whether and how p53 also regulates gluconeogenesis is less clear. Here, we report that p53 efficiently down-regulates the expression of phosp...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Zhang, Ping, Tu, Bo, Wang, Hua, Cao, Ziyang, Tang, Ming, Zhang, Chaohua, Gu, Bo, Li, Zhiming, Wang, Lina, Yang, Yang, Zhao, Ying, Wang, Haiying, Luo, Jianyuan, Deng, Chu-Xia, Gao, Bin, Roeder, Robert G., Zhu, Wei-Guo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4115576/
https://ncbi.nlm.nih.gov/pubmed/25009184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1411026111
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados