Membrane Remodeling Induced by the Dynamin Related Protein Drp1 Stimulates Bax Oligomerization

In response to many apoptotic stimuli, oligomerization of Bax is essential for mitochondrial outer membrane permeabilization and the ensuing release of cytochrome c. These events are accompanied by mitochondrial fission that appears to require Drp1, a large GTPase of the dynamin superfamily. Loss of...

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Detalhes bibliográficos
Main Authors: Montessuit, Sylvie, Somasekharan, Syam Prakash, Terrones, Oihana, Lucken-Ardjomande, Safa, Herzig, Sébastien, Schwarzenbacher, Robert, Manstein, Dietmar, Bossy-Wetzel, Ella, Basañez, Gorka, Meda, Paolo, Martinou, Jean-Claude
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4115189/
https://ncbi.nlm.nih.gov/pubmed/20850011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.08.017
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