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Specific Interaction with Cardiolipin Triggers Functional Activation of Dynamin-Related Protein 1
Dynamin-Related Protein 1 (Drp1), a large GTPase of the dynamin superfamily, is required for mitochondrial fission in healthy and apoptotic cells. Drp1 activation is a complex process that involves translocation from the cytosol to the mitochondrial outer membrane (MOM) and assembly into rings/spira...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4103857/ https://ncbi.nlm.nih.gov/pubmed/25036098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102738 |
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