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Cardiolipin or MTCH2 can serve as tBID receptors during apoptosis
During apoptosis, proapoptotic BAX and BAK trigger mitochondrial outer membrane (MOM) permeabilization by a mechanism that is not yet fully understood. BH3-only proteins such as tBID, together with lipids of the MOM, are thought to play a key role in BAX and BAK activation. In particular, cardiolipi...
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| Published in: | Cell Death Differ |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4946884/ https://ncbi.nlm.nih.gov/pubmed/26794447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.166 |
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