Cardiolipin or MTCH2 can serve as tBID receptors during apoptosis

During apoptosis, proapoptotic BAX and BAK trigger mitochondrial outer membrane (MOM) permeabilization by a mechanism that is not yet fully understood. BH3-only proteins such as tBID, together with lipids of the MOM, are thought to play a key role in BAX and BAK activation. In particular, cardiolipi...

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Detalles Bibliográficos
Publicado en:Cell Death Differ
Main Authors: Raemy, E, Montessuit, S, Pierredon, S, van Kampen, A H, Vaz, F M, Martinou, J-C
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Original Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4946884/
https://ncbi.nlm.nih.gov/pubmed/26794447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.166
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