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Timely Activation of Budding Yeast APC(Cdh1) Involves Degradation of Its Inhibitor, Acm1, by an Unconventional Proteolytic Mechanism
Regulated proteolysis mediated by the ubiquitin proteasome system is a fundamental and essential feature of the eukaryotic cell division cycle. Most proteins with cell cycle-regulated stability are targeted for degradation by one of two related ubiquitin ligases, the Skp1-cullin-F box protein (SCF)...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4114781/ https://ncbi.nlm.nih.gov/pubmed/25072887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103517 |
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