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Timely Activation of Budding Yeast APC(Cdh1) Involves Degradation of Its Inhibitor, Acm1, by an Unconventional Proteolytic Mechanism

Regulated proteolysis mediated by the ubiquitin proteasome system is a fundamental and essential feature of the eukaryotic cell division cycle. Most proteins with cell cycle-regulated stability are targeted for degradation by one of two related ubiquitin ligases, the Skp1-cullin-F box protein (SCF)...

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Detalhes bibliográficos
Main Authors: Melesse, Michael, Choi, Eunyoung, Hall, Hana, Walsh, Michael J., Geer, M. Ariel, Hall, Mark C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4114781/
https://ncbi.nlm.nih.gov/pubmed/25072887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103517
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