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Synthetic studies on lemonomycin: construction of the tetracyclic core

A substrate-induced stereocontrol strategy was used to gain access to the tetracyclic core of (-)-lemonomycin. An advanced intermediate was prepared from a known substituted tyrosinol through a 16-step sequence, which involved a Pictet-Spengler reaction, a [3+2] dipolar cycloaddition and an enamide...

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Sonraí Bibleagrafaíochta
Main Authors: Jiménez-Somarribas, Alberto, Williams, Robert M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4114395/
https://ncbi.nlm.nih.gov/pubmed/25083002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2013.05.009
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