Bystander chronic infection negatively impacts development of CD8(+) T cell memory

Epidemiological evidence suggests that chronic infections impair immune responses to unrelated pathogens and vaccines. The underlying mechanisms, however, are unclear and distinguishing effects on priming versus development of immunological memory has been challenging. We investigated whether bystan...

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Detalhes bibliográficos
Main Authors: Stelekati, Erietta, Shin, Haina, Doering, Travis A., Dolfi, Douglas V., Ziegler, Carly G., Beiting, Daniel P., Dawson, Lucas, Liboon, Jennifer, Wolski, David, Ali, Mohammed-Alkhatim A., Katsikis, Peter D., Shen, Hao, Roos, David S., Haining, W. Nicholas, Lauer, Georg M., Wherry, E. John
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4114317/
https://ncbi.nlm.nih.gov/pubmed/24837104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2014.04.010
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