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Theoretical study of genetic variability, assuming stepwise production of neutral and very slightly deleterious mutations.

Mathematical treatments are presented that enable us to compute the amount of genetic variability maintained in a finite population, assuming that mutations occur in stepwise fashion and that both selectively neutral and slightly deleterious alleles are involved. Two numerical examples show that, if...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Maruyama, T, Kimura, M
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1978
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411369/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/273253/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.2.919
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