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Theoretical study of genetic variability, assuming stepwise production of neutral and very slightly deleterious mutations.

Mathematical treatments are presented that enable us to compute the amount of genetic variability maintained in a finite population, assuming that mutations occur in stepwise fashion and that both selectively neutral and slightly deleterious alleles are involved. Two numerical examples show that, if...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Maruyama, T, Kimura, M
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1978
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411369/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/273253/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.2.919
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