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Theoretical study of genetic variability, assuming stepwise production of neutral and very slightly deleterious mutations.

Mathematical treatments are presented that enable us to compute the amount of genetic variability maintained in a finite population, assuming that mutations occur in stepwise fashion and that both selectively neutral and slightly deleterious alleles are involved. Two numerical examples show that, if...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Maruyama, T, Kimura, M
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1978
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411369/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/273253/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.2.919
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