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Irradiation facilitates the inhibitory effect of the heat shock protein 90 inhibitor NVP-BEP800 on the proliferation of malignant glioblastoma cells through attenuation of the upregulation of heat shock protein 70

The present study aimed to investigate the effect of NVP-BEP800, a novel heat shock protein (Hsp) 90 inhibitor of the 2-aminothieno[2,3-d]pyrimidine class, in combination with radiation on glioblastoma cells. T98G human glioblastoma cells were treated with dimethyl sulfoxide (DMSO), NVP-BEP800, NVP-...

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Détails bibliographiques
Auteurs principaux: WU, JIANYUE, WANG, WEIMIN, SHAO, QIN, XIAO, GUOMIN, CHENG, JUN, YUAN, YUNPENG, ZHANG, MEI
Format: Artigo
Langue:Inglês
Publié: D.A. Spandidos 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113540/
https://ncbi.nlm.nih.gov/pubmed/25120620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2014.1800
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