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Therapeutic strategies in inflammasome mediated diseases of the liver

Tissue stress and cell death result in inflammation even in the absence of pathogens. Such sterile inflammation is dependent on a cytosolic complex of proteins inside immune cells termed the inflammasome. This complex converts two groups of extracellular signals into an inflammatory response via act...

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Autores principales: Hoque, Rafaz, Vodovotz, Yoram, Mehal, Wajahat
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113326/
https://ncbi.nlm.nih.gov/pubmed/23266490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2012.12.017
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