Activation of N-methyl-d-aspartate receptor downregulates inflammasome activity and liver inflammation via a β-arrestin-2 pathway

Activation of the cytosolic inflammasome machinery is responsible for acute and chronic liver inflammation, but little is known about its regulation. The N-methyl-d-aspartate (NMDA) receptor families are heterotetrameric ligand-gated ion channels that are activated by a range of metabolites, includi...

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Detalhes bibliográficos
Main Authors: Farooq, Ahmad, Hoque, Rafaz, Ouyang, Xinshou, Farooq, Ahsan, Ghani, Ayaz, Ahsan, Kaimul, Guerra, Mateus, Mehal, Wajahat Zafar
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Inflammation/Immunity/Mediators
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187065/
https://ncbi.nlm.nih.gov/pubmed/25104498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00073.2014
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