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Downregulation of Sirt1 as aging change in advanced heart failure
BACKGROUND: In congestive heart failure the balance between cell death and cell survival in cardiomyocytes is compromised. Sirtuin 1 (Sirt1) activates cell survival machinery and has been shown to be protective against ischemia/reperfusion injury in murine heart. The role of Sirt1 in heart failure,...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4113120/ https://ncbi.nlm.nih.gov/pubmed/24913149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-21-57 |
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