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Families or Unrelated: The Evolving Debate in Genetic Association Studies

To help uncover the genetic determinants of complex disease, a scientist often designs an association study using either unrelated subjects or family members within pedigrees. But which of these two subject recruitment paradigms is preferable? This editorial addresses the debate over the relative me...

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Autori principali: Fardo, David W., Charnigo, Richard, Epstein, Michael P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112473/
https://ncbi.nlm.nih.gov/pubmed/25077036
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