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Controlling Population Structure in Human Genetic Association Studies with Samples of Unrelated Individuals

In genetic studies, associations between genotypes and phenotypes may be confounded by unrecognized population structure and/or admixture. Studies have shown that even in European populations, which are thought to be relatively homogeneous, population stratification exists and can affect the validit...

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Detalhes bibliográficos
Main Authors: LIU, NIANJUN, ZHAO, HONGYU, PATKI, AMIT, LIMDI, NITA A., ALLISON, DAVID B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269890/
https://ncbi.nlm.nih.gov/pubmed/22308192
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