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High risk of tobacco-related cancers in CDKN2A mutation-positive melanoma families
BACKGROUND: Germline mutations in the tumour suppressor gene CDKN2A occur in 5–20% of familial melanoma cases. A single founder mutation, p.Arg112dup, accounts for the majority of CDKN2A mutations in Swedish carriers. In a national program, carriers of p.Arg112dup mutation have been identified. The...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BMJ Publishing Group
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4112445/ https://ncbi.nlm.nih.gov/pubmed/24935963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmedgenet-2014-102320 |
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