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Binding and release of eukaryotic initiation factor eIF-2 and GTP during protein synthesis initiation.
The eukaryotic initiation factor eIF-2 forms a ternary complex with Met-tRNAf and GTP. This complex binds to the 40S ribosomal subunit in the absence of mRNA and mRNA binding factors. Highly purified eIF-2 from rabbit reticulocytes was labeled with 125I by using the Bolton-Hunter reagent or with [ga...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1978
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411214/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/272635/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.1.204 |
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