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Binding and release of eukaryotic initiation factor eIF-2 and GTP during protein synthesis initiation.

The eukaryotic initiation factor eIF-2 forms a ternary complex with Met-tRNAf and GTP. This complex binds to the 40S ribosomal subunit in the absence of mRNA and mRNA binding factors. Highly purified eIF-2 from rabbit reticulocytes was labeled with 125I by using the Bolton-Hunter reagent or with [ga...

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Foilsithe in:Proc Natl Acad Sci U S A
Main Authors: Trachsel, H, Staehelin, T
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 1978
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411214/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/272635/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.1.204
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