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Inhibition of histone deacetylases enhances DNA damage repair in SCNT embryos

Recent studies have shown that DNA damage affects embryo development and also somatic cell reprogramming into induced pluripotent stem (iPS) cells. It has been also shown that treatment with histone deacetylase inhibitors (HDACi) improves development of embryos produced by somatic cell nuclear trans...

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Detalles Bibliográficos
Main Authors: Bohrer, Rodrigo Camponogara, Duggavathi, Raj, Bordignon, Vilceu
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111705/
https://ncbi.nlm.nih.gov/pubmed/24841373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.29215
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