Dyrk1A induces pancreatic β cell mass expansion and improves glucose tolerance

Type 2 diabetes is caused by a limited capacity of insulin-producing pancreatic β cells to increase their mass and function in response to insulin resistance. The signaling pathways that positively regulate functional β cell mass have not been fully elucidated. DYRK1A (also called minibrain/MNB) is...

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Hlavní autoři: Rachdi, Latif, Kariyawasam, Dulanjalee, Aïello, Virginie, Herault, Yann, Janel, Nathalie, Delabar, Jean-Maurice, Polak, Michel, Scharfmann, Raphaël
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111677/
https://ncbi.nlm.nih.gov/pubmed/24870561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.29250
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