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Association between Polymorphisms in the TSHR Gene and Graves' Orbitopathy

BACKGROUND: Graves' orbitopathy (GO) as well as Graves' disease (GD) hyperthyroidism originate from an autoimmune reaction against the common auto-antigen, thyroid-stimulating hormone receptor (TSHR). GO phenotype is associated with environmental risk factors, mainly nicotinism, as well as...

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Auteurs principaux: Jurecka-Lubieniecka, Beata, Ploski, Rafal, Kula, Dorota, Szymanski, Konrad, Bednarczuk, Tomasz, Ambroziak, Urszula, Hasse-Lazar, Kornelia, Hyla-Klekot, Lidia, Tukiendorf, Andrzej, Kolosza, Zofia, Jarzab, Barbara
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111286/
https://ncbi.nlm.nih.gov/pubmed/25061884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102653
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